ORAL CHOLESTYRAMINE FORMULATION AND USE THEREOF

The invention relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a diffusion-controlled inner coating and an enteric outer coating. The invention also relates to the use of this formulation in the...

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Bibliographic Details
Main Authors GILLBERG, PER-GORAN, ELVERSSON, JESSICA, GUSTAFSSON, NILS OVE, LINDBERG, NILS-OLOF
Format Patent
LanguageEnglish
French
Published 02.01.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a diffusion-controlled inner coating and an enteric outer coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption. L'invention concerne une formulation orale pour l'administration ciblée de cholestyramine au côlon comprenant une pluralité de pastilles de cholestyramine qui sont revêtues d'un revêtement interne à diffusion contrôlée et d'un enrobage externe gastro-résistant. L'invention concerne en outre l'utilisation de cette formulation dans le traitement de la malabsorption des acides biliaires.
Bibliography:Application Number: CA20173011619