COMPOUNDS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS

The present invention provides compounds of formula (I) (I) wherein A, R1, R2 and R3 are as described herein, as well as pharmaceutically acceptable salts thereof for use in the treatment, prevention and/or delay of progression of amyotrophic lateral sclerosis (ALS). Further the present invention is...

Full description

Saved in:
Bibliographic Details
Main Authors METZGER, FRIEDRICH, MCCARTHY, KATHLEEN DOROTHY, RATNI, HASANE
Format Patent
LanguageEnglish
French
Published 18.05.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present invention provides compounds of formula (I) (I) wherein A, R1, R2 and R3 are as described herein, as well as pharmaceutically acceptable salts thereof for use in the treatment, prevention and/or delay of progression of amyotrophic lateral sclerosis (ALS). Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments. La présente invention concerne des composés de formule (I) (I) dans laquelle A, R1, R2 et R3 sont tels que décrits ici, ainsi que les sels pharmaceutiquement acceptables de ceux-ci pour leur utilisation, dans le traitement, la prévention et/ou le ralentissement de la progression de la sclérose latérale amyotrophique (SLA). L'invention concerne également la fabrication des composés représentés par la formule (I), des compositions pharmaceutiques les comprenant, et leur utilisation en tant que médicaments.
Bibliography:Application Number: CA20162996657