ENZYME INTERACTING AGENTS

The present disclosure relates generally, but not exclusively, to compounds and their use as enzyme interacting agents, in particular, agents which interact with one or more enzymes in the sphingolipid biosynthesis pathway. The disclosure further relates to the use of such 5 compounds as research to...

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Main Authors FLYNN, BERNARD LUKE, PITMAN, MELISSA ROSE, SCULLINO, CARMEN VITTORIA, PITSON, STUART MAXWELL, AURELIO, LUIGI, WANG, BING HUI
Format Patent
LanguageEnglish
French
Published 30.12.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present disclosure relates generally, but not exclusively, to compounds and their use as enzyme interacting agents, in particular, agents which interact with one or more enzymes in the sphingolipid biosynthesis pathway. The disclosure further relates to the use of such 5 compounds as research tools, use in therapy, to compositions and agents comprising said compounds, and to methods of treatment using said compounds. Cette divulgation concerne, de façon générale, mais pas exclusive, des composés et leur utilisation à titre d'agents d'interaction avec des enzymes, en particulier, des agents qui interagissent avec une ou plusieurs enzymes dans la voie de biosynthèse des sphingolipides. L'utilisation de ces composés à titre d'outils de recherche, en thérapie, des compositions et des agents contenant lesdits composés, et des méthodes de traitement utilisant lesdits composés sont en outre décrits.
Bibliography:Application Number: CA20152990028