PYRAZOLE DERIVATIVES USEFUL AS 5-LIPOXYGENASE ACTIVATING PROTEIN (FLAP) INHIBITORS

The present application relates to novel compounds of formula (I) to their utility in treating and/or preventing clinical conditions including cardiovascular diseases (CVD), to methods for their therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compo...

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Main Authors EMTENAS, HANS FREDRIK, BRODDEFALK, JOHAN OLOF, ULANDER, LARS JOHAN ANDREAS, LEMURELL, MALIN ANITA, PLOWRIGHT, ALLEYN THOMAS, PETTERSEN, DANIEL TOR, GRANBERG, KENNETH LARS
Format Patent
LanguageEnglish
French
Published 27.06.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present application relates to novel compounds of formula (I) to their utility in treating and/or preventing clinical conditions including cardiovascular diseases (CVD), to methods for their therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds. La présente invention concerne de nouveaux composés de formule (I), leur utilité dans le traitement et/ou la prévention de conditions cliniques, notamment des maladies cardiovasculaires (CDV), des procédés pour leur utilisation thérapeutique, des compositions pharmaceutiques les contenant et des procédés pour la préparation de tels composés.
Bibliography:Application Number: CA20162983668