ACYLATED 4-AMINOPIPERIDINES AS INHIBITORS OF SERINE PALMITOYLTRANSFERASE

The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease) Il est décrit un composé qui peut être utile aux fins de traitem...

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Bibliographic Details
Main Authors IMAMURA, SHINICHI, ASANO, YASUTOMI, SANO, OSAMU, KURASAWA, OSAMU, HIRATA, YASUHIRO, TANAKA, YUTA, KITAMURA, SHUJI, KOJIMA, TAKUTO, IWAMURA, NAOKI, YONEMORI, KAZUKO, MIYAMOTO, YASUFUMI, ARAI, RYOSUKE, WONG, TZU-TSHIN, SAITO, BUNNAI
Format Patent
LanguageEnglish
French
Published 27.10.2016
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease) Il est décrit un composé qui peut être utile aux fins de traitement ou de prévention de maladies liées à la sérine palmitoyltransférase, y compris le cancer et les maladies congénitales associées à l'accumulation de sphingolipides (y compris la maladie de Niemann-Pick).
Bibliography:Application Number: CA20162983391