OXO-PYRIDINE-DERIVATIVES AS FACTOR XIA INHIBITORS FOR THE TREATMENT OF THROMBOSIS

The invention relates to substituted oxo-pyridine derivatives and methods for the production thereof, as well as to the use thereof in the production of medicaments for treating and/or preventing diseases, especially diseases of the cardiovascular system, preferably thrombotic or thromboembolic dise...

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Main Authors JIMENEZ NUNEZ, ELOISA, HILLISCH, ALEXANDER, ROHRIG, SUSANNE, TERSTEEGEN, ADRIAN, STAMPFUSS, JAN, TELLER, HENRIK, SCHLEMMER, KARL-HEINZ, HEITMEIER, STEFAN
Format Patent
LanguageEnglish
French
Published 22.09.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to substituted oxo-pyridine derivatives and methods for the production thereof, as well as to the use thereof in the production of medicaments for treating and/or preventing diseases, especially diseases of the cardiovascular system, preferably thrombotic or thromboembolic diseases, as well as oedemas, and also ophthalmological diseases. L'invention concerne des dérivés d'oxopyridine substitués et des procédés pour les préparer ainsi que leur utilisation pour produire des médicaments destinés au traitement et/ou à la prophylaxie de maladies, en particulier de maladies cardiovasculaires, de préférence de maladies thrombotiques ou encore de maladies thromboemboliques et de l'dème ainsi que de maladies ophtalmiques.
Bibliography:Application Number: CA20162979937