NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING

The present invention relates generally to labeled and unlabled cleavable terminating groups and methods for DNA sequencing and other types of DNA analysis. More particularly, the invention relates in part to nuclotides and nucleosides with chemically cleavable, photocleavable, enzymatically cleavab...

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Bibliographic Details
Main Authors HERSH, MEGAN N, STUPI, BRIAN P, LITOSH, VLADISLAV A, WU, WEIDONG, METZKER, MICHAEL L
Format Patent
LanguageEnglish
French
Published 07.07.2020
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Summary:The present invention relates generally to labeled and unlabled cleavable terminating groups and methods for DNA sequencing and other types of DNA analysis. More particularly, the invention relates in part to nuclotides and nucleosides with chemically cleavable, photocleavable, enzymatically cleavable, or non-photocleavable groups and methods for their use in DNA sequencing and its application in biomedical research. La présente invention concerne, de manière générale, des groupes de terminaison clivables, marqués et non marqués, et des procédés pour le séquençage de lADN et dautres types danalyses de lADN. Plus particulièrement, linvention concerne en partie des nucléotides et des nucléosides ayant des groupes chimiquement clivables, photoclivables, clivables par voie enzymatique, ou non photoclivables et des procédés pour leur utilisation dans le séquençage de lADN et leur application en recherche biomédicale.
Bibliography:Application Number: CA20092979146