SUBSTRATES AND OPTICAL SYSTEMS AND METHODS OF USE THEREOF

• Main Authors: BAYANDORIAN, HOVIG, ZHONG, CHENG FRANK, FOQUET, MATHIEU, LUNDQUIST, PAUL, KORLACH, JONAS
• Format: Patent
• Language: English; French
• Published: 07.01.2020
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; NANOTECHNOLOGY; OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS; OPTICS; PERFORMING OPERATIONS; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; SPIRITS; TESTING; TRANSPORTING; VINEGAR; WINE

This specification provides substrates for use in various applications, including single-molecule analytical reactions. Methods for propagating optical energy within a substrate are provided. Devices comprising waveguide substrates and dielectric omnidirectional reflectors are provided. Waveguide substrates with improved uniformity of optical energy intensity across one or more waveguides and enhanced waveguide illumination efficiency within an analytic detection region of the arrays are provided. La présente invention concerne des substrats destinés à être utilisés dans diverses applications, y compris des réactions analytiques à molécule unique. Linvention concerne également des procédés de propagation dénergie optique dans un substrat. Des dispositifs comprenant des substrats de guide dondes et un diélectrique omnidirectionnel des réflecteurs sont prévus. Linvention concerne également des substrats de guide dondes présentant une uniformité améliorée de lintensité de lénergie optique à travers un ou plusieurs guides dondes et un rendement de léclairage de guide dondes amélioré dans une région de détection analytique des réseaux.