THIENO[2,3-C]PYRROL-4-ONE DERIVATIVES AS ERK INHIBITORS

The present invention provides thieno[2,3-c]pyrrol-4-one compounds that inhibit activity of extracellular-signal-regulated kinase (ERK) and may be useful in the treatment of cancer. La présente invention concerne des composés de thiéno[2,3-c]pyrrol-4-one qui inhibent l'activité de la kinase rég...

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Bibliographic Details
Main Authors RODRIGUEZ, MICHAEL JOHN, CORTEZ, GUILLERMO S, JOSEPH, SAJAN, ZHAO, GAIYING, MCMILLEN, WILLIAM T, MCLEAN, JOHNATHAN ALEXANDER
Format Patent
LanguageEnglish
French
Published 18.06.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides thieno[2,3-c]pyrrol-4-one compounds that inhibit activity of extracellular-signal-regulated kinase (ERK) and may be useful in the treatment of cancer. La présente invention concerne des composés de thiéno[2,3-c]pyrrol-4-one qui inhibent l'activité de la kinase régulée par un signal extracellulaire (ERK) et peuvent être utiles dans le traitement du cancer.
Bibliography:Application Number: CA20152966559