THERAPEUTIC COMPOUNDS AS INHIBITORS OF THE OREXIN-1 RECEPTOR

The present invention relates to compounds that are inhibitors of the orexin-1 receptor. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their us...

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Bibliographic Details
Main Authors WATSON, MARTIN JOHN, NOWAK, THORSTEN, MARTIN, BARRIE PHILLIP, BLANEY, EMMA LOUISE
Format Patent
LanguageEnglish
French
Published 01.08.2023
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds that are inhibitors of the orexin-1 receptor. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with orexin-1 receptor activity. La présente invention concerne des composés qui sont des inhibiteurs du récepteur de l'orexine-1. Ces composés sont représentés par la formule développée I telle que définie ici. La présente invention concerne également des procédés de préparation de ces composés, des compositions pharmaceutiques en comprenant et leur utilisation dans le traitement de maladies ou d'affections associées à l'activité du récepteur de l'orexine-1.
Bibliography:Application Number: CA20152959942