ARRAYS OF INTEGRATED ANALYTICAL DEVICES

Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The devices allow the h...

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Bibliographic Details
Main Authors SAXENA, RAVI, GROT, ANNETTE, LUNDQUIST, PAUL
Format Patent
LanguageEnglish
French
Published 03.03.2016
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Summary:Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The devices allow the highly sensitive discrimination of optical signals using features such as spectra, amplitude, and time resolution, or combinations thereof. The devices include an integrated diffractive beam shaping element that provides for the spatial separation of light emitted from the optical reactions. La présente invention concerne des réseaux de dispositifs d'analyse intégrés et leurs procédés de fabrication. Les réseaux sont utiles dans l'analyse de réactions optiques hautement multiplexées en grands nombres à des densités élevées, comprenant des réactions biochimiques, telles que des réactions de séquençage d'acide nucléique. Les dispositifs permettent la discrimination très sensible de signaux optiques au moyen de caractéristiques telles que les spectres, l'amplitude, et la résolution temporelle, ou des combinaisons de celles-ci. Les dispositifs comprennent un élément de formation de faisceau diffractif qui permet la séparation spatiale de la lumière émise à partir des réactions optiques.
Bibliography:Application Number: CA20152959518