POLYCYCLIC HERG ACTIVATORS

The present invention provides a compound of formula I, in which R1, R2, X and R3 are defined in the Summary of the Invention, or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a...

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Main Authors CODY, EMMA, DAY, ROBERT FRANCI, QIAN, MING, ZECRI, FREDERIC, BEBERNITZ, GREGORY RAYMOND, WHITEHEAD, LEWIS, ZABAWA, THOMAS, PATEL, TAJESH JAYPRAKASH
Format Patent
LanguageEnglish
French
Published 22.10.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a compound of formula I, in which R1, R2, X and R3 are defined in the Summary of the Invention, or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. La présente invention concerne un composé de formule I, dans laquelle R1, R2, X et R3 sont définis dans le résumé de l'invention, ou un sel pharmaceutiquement acceptable de celui-ci; un procédé de fabrication des composés de l'invention, et ses utilisations thérapeutiques. La présente invention concerne également une combinaison de composants pharmacologiquement actifs et d'une composition pharmaceutique.
Bibliography:Application Number: CA20152945539