MMP-8 ACTIVATION PRODUCT, ITS DETERMINATION AND USE

The present invention relates to a novel MMP-8 activation product such as a MMP-8 middle-part activation product. The invention also relates to detecting such a MMP-8 activation product or activated MMP-8 fragments in a biological sample derived from a subject and to the use thereof for diagnosing d...

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Main Authors KORVUO, ARMI, MANTYLA, PAIVI, TIISALA, SINIKKA, MAIER, KURT, SORSA, TIMO, GIESELMANN, DIRK-ROLF, RAMAN, ISMO
Format Patent
LanguageEnglish
French
Published 03.09.2015
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Summary:The present invention relates to a novel MMP-8 activation product such as a MMP-8 middle-part activation product. The invention also relates to detecting such a MMP-8 activation product or activated MMP-8 fragments in a biological sample derived from a subject and to the use thereof for diagnosing diseases which relate to abnormal or elevated levels of activated MMP-8. La présente invention concerne un nouveau produit d'activation de MMP -8, comme un produit d'activation de la partie médiane de MMP-8. L'invention concerne également la détection d'un tel produit d'activation de MMP-8 ou de fragments de MMP-8 activés dans un échantillon biologique dérivé d'un sujet et l'utilisation de celui-ci pour le diagnostic de maladies qui sont associées à des niveaux anormaux ou élevés de MMP-8.
Bibliography:Application Number: CA20152940588