SUBSTITUTED AZETIDINE COMPOUNDS AND THEIR USE AS FACTOR XIA OR KALLIKREIN INHIBITORS

The present invention provides compounds and compositions that inhibit Factor XIa or kallikrein and methods of using these compounds and composition. The compounds may include compounds of the fommla Il est décrit des composés et des compositions qui inhibent le facteur XIa ou la kallicréine, ainsi...

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Main Authors POEL, TONI J, STEWART, CATHERINE A, GADWOOD, ROBERT C, MELNICK, MICHAEL J, NAVIA, MANUEL, CHRUSCIEL, ROBERT A, STASSEN, FRANS L, HAYWARD, NEIL J
Format Patent
LanguageEnglish
French
Published 13.02.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides compounds and compositions that inhibit Factor XIa or kallikrein and methods of using these compounds and composition. The compounds may include compounds of the fommla Il est décrit des composés et des compositions qui inhibent le facteur XIa ou la kallicréine, ainsi que des méthodes d'utilisation desdits composés et compositions. Les composés peuvent comprendre des composés de la formule
Bibliography:Application Number: CA20152938884