DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA
Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORy. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) a...
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| Main Authors | , , , , , , , , , , , , , |
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| Format | Patent |
| Language | English French |
| Published |
07.03.2023
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORy. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.
L'invention concerne de nouveaux composés de formule (I) : des sels pharmaceutiquement acceptables de ceux-ci, et des compositions pharmaceutiques de ceux-ci, qui sont utiles dans le traitement de maladies et de troubles à médiation par ROR?. L'invention concerne également des compositions pharmaceutiques comprenant les nouveaux composés de formule (I) et des procédés pour leur utilisation dans le traitement d'un ou de plusieurs troubles ou maladies inflammatoires, métaboliques, auto-immun(e)s et autres. |
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| AbstractList | Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORy. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.
L'invention concerne de nouveaux composés de formule (I) : des sels pharmaceutiquement acceptables de ceux-ci, et des compositions pharmaceutiques de ceux-ci, qui sont utiles dans le traitement de maladies et de troubles à médiation par ROR?. L'invention concerne également des compositions pharmaceutiques comprenant les nouveaux composés de formule (I) et des procédés pour leur utilisation dans le traitement d'un ou de plusieurs troubles ou maladies inflammatoires, métaboliques, auto-immun(e)s et autres. |
| Author | LIU, ZHIJIE DILLARD, LAWRENCE WAYNE MARCUS, ANDREW ZHENG, YAJUN ZHAO, WEI FAN, YI ZHUANG, LINGHANG DONG, CHENGGUO CLAREMON, DAVID A TICE, COLIN M YUAN, JING LOTESTA, STEPHEN D JIA, LANQI SINGH, SURESH B |
| Author_xml | – fullname: CLAREMON, DAVID A – fullname: LOTESTA, STEPHEN D – fullname: YUAN, JING – fullname: ZHUANG, LINGHANG – fullname: SINGH, SURESH B – fullname: TICE, COLIN M – fullname: MARCUS, ANDREW – fullname: LIU, ZHIJIE – fullname: ZHENG, YAJUN – fullname: FAN, YI – fullname: JIA, LANQI – fullname: ZHAO, WEI – fullname: DILLARD, LAWRENCE WAYNE – fullname: DONG, CHENGGUO |
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| DocumentTitleAlternate | INHIBITEURS DE ROR-GAMMA A BASE DE DIHYDROPYRROLOPYRIDINE |
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| Snippet | Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the... |
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| Title | DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA |
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