SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS AS RXR AGONISTS

The present invention relates to certain substituted bicyclic compounds of formula (I) that are agonists of RXR and which are therefore useful in the treatment of certain disorders that can be prevented or treated by activation of this receptor. In addition the invention relates to the compounds, me...

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Bibliographic Details
Main Authors RAO, JAGANNATH MADANAHALLI RANGANATH, GUDLA, CHANDRA SEKHAR, RANGA, MADHAVAN GURRAM
Format Patent
LanguageEnglish
French
Published 17.10.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to certain substituted bicyclic compounds of formula (I) that are agonists of RXR and which are therefore useful in the treatment of certain disorders that can be prevented or treated by activation of this receptor. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders. La présente invention se rapporte à certains composés bicycliques substitués de formule (I), qui sont des agonistes de RXR et sont par conséquent utiles dans le traitement de certains troubles pouvant être empêchés ou traités par l'activation de ce récepteur. L'invention concerne également des composés, leurs méthodes de préparation, des compositions pharmaceutiques contenant ces composés et des utilisations de ces composés dans le traitement de certains troubles.
Bibliography:Application Number: CA20152936162