MEK INHIBITORS AND METHODS OF THEIR USE

Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors. Also disclosed are pharmaceutical compositions containing such compounds. Des composés sont divulgués de formule (I) et leurs sels pharmaceutiquement acceptables et l...

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Main Authors KOLTUN, ELENA, BUSSENIUS, JOERG, KENNEDY, ABIGAIL R, MANALO, JEAN-CLAIRE LIMUN, PETO, CSABA J, DUBENKO, LARISA, AAY, NAING, CURTIS, JEFFRY KIMO, BLAZEY, CHARLES M, COSTANZO, SIMONA, JOSHI, ANAGHA ABHIJIT, BOWLES, OWEN JOSEPH, KIM, ANGIE INYOUNG, ANAND, NEEL KUMAR, RICE, KENNETH D, TSANG, TSZE H, DEFINA, STEVEN CHARLES
Format Patent
LanguageEnglish
French
Published 24.09.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors. Also disclosed are pharmaceutical compositions containing such compounds. Des composés sont divulgués de formule (I) et leurs sels pharmaceutiquement acceptables et leurs solvates. De tels composés sont des inhibiteurs de MEK. Des compositions renfermant de tels composés sont divulguées.
Bibliography:Application Number: CA20062927656