PHARMACEUTICAL DOSAGE FORMS CONTAINING SODIUM-1-[6-(MORPHOLIN-4-YL)PYRIMIDIN-4-YL]-4-(1H-1,2,3-TRIAZOL-1-YL)-1H-PYRAZOL-5-OLATE

• Main Authors: BENKE, KLAUS, NEUMANN, HEIKE, WINTER, GABRIELE, FORMELL, MICHAEL
• Format: Patent
• Language: English; French
• Published: 23.04.2015
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The invention relates to solid pharmaceutical dosage forms that can be orally administered, containing sodium-1-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-olate (active ingredient (I)), characterized in that the active ingredient (I) is released. The invention further relates to methods for producing said dosage forms, to the use of said dosage forms as drugs, and to the use of said dosage forms for the prophylaxis, secondary prophylaxis, or treatment of diseases, in particular cardiovascular diseases, cardiac insufficiency, anemia, chronic kidney diseases, and renal failure. L'invention concerne des formes galéniques pharmaceutiques pour administration orale contenant du sodium 1-[6-{morpholine-4-yl)pyrimidine-4-yl]-4-(1H-1,2,3- triazol-1-yl)-1H-pyrazol-5-olate (principe actif (I). Selon l'invention, le principe actif (I) est libéré. L'invention concerne également un procédé de production desdites formes galéniques, leur utilisation comme médicament, ainsi que leur utilisation pour la prophylaxie, la prophylaxie secondaire ou le traitement de maladies, en particulier les maladies cardiovasculaires, l'insuffisance cardiaque, l'anémie, les maladies rénales chroniques et l'insuffisance rénale.