MULTISPECIFIC ANTIBODIES, MULTISPECIFIC ACTIVATABLE ANTIBODIES AND METHODS OF USING THE SAME

The invention relates generally to multispecific antibodies and to multispecific activatable antibodies that specifically bind to two or more different antigens or epitopes, as well as to methods of making and using these multispecific antibodies and/or multispecific activatable antibodies in a vari...

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Bibliographic Details
Main Authors LOWMAN, HENRY BERNARD, HOSTETTER, DANIEL ROBERT, WEST, JAMES WILLIAM, LA PORTE, SHERRY LYNN, IRVING, BRYAN ALLEN, WONG, CHIHUNT
Format Patent
LanguageEnglish
French
Published 29.01.2015
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The invention relates generally to multispecific antibodies and to multispecific activatable antibodies that specifically bind to two or more different antigens or epitopes, as well as to methods of making and using these multispecific antibodies and/or multispecific activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications. L'invention concerne de manière générale des anticorps multispéciiques et des anticorps activables multispécifiques qui se lient spécifiquement à au moins deux antigènes ou épitopes différents, ainsi que des méthodes de préparation et d'utilisation de ces anticorps multispécifiques et/ou anticorps activables multispécifiques dans diverses indications thérapeutiques, diagnostiques et prophylactiques.
Bibliography:Application Number: CA20142918795