TRICYCLIC PYRROLE COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS

The invention refers to compounds of general formula (I) wherein the variables take the various meanings, pharmaceutical compositions containing them and their use in medicine: The compounds have shown to be useful in therapy as angiogenesis inhibitors. The compounds are isolated from the fermentati...

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Main Authors CALVO PELAZ, BELINDA, MEDINA TORRES, MIGUEL ANGEL, MARTINEZ INSUA, MARTA, SANCHEZ LOPEZ, JOSE MARIA, RODRIGUEZ QUESADA, ANA, FERNANDEZ MEDARDE, ANTONIO, CANEDO HERNANDEZ, LIBRADA MARIA, GARCIA CABALLERO, MELISSA, VINUESA-NAVARRO, MARIA DE LOS ANGELES
Format Patent
LanguageEnglish
French
Published 15.01.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention refers to compounds of general formula (I) wherein the variables take the various meanings, pharmaceutical compositions containing them and their use in medicine: The compounds have shown to be useful in therapy as angiogenesis inhibitors. The compounds are isolated from the fermentation broth of a fungal strain Paraconiothyrium sp., or are derivatives thereof.
Bibliography:Application Number: CA20142917744