5,6,7,8-TETRAHYDROPYRAZINO[2,3-C]PYRIDAZINE COMPOUNDS AND THE USE THEREOF TO TREAT ONCOLOGICAL DISEASES

The invention relates to novel chemical compounds of general formula I, in which L A, L B, L C, ring A, ring B, R A, R B, R C,R D,R E and R F have are defined in the description, and which are protein kinases inhibitors. The invention also relates to pharmaceutical compositions containing said compo...

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Bibliographic Details
Main Authors CHILOV, GERMES GRIGORIEVICH, STROILOV, VIKTOR SERGEEVICH, STROGANOV, OLEG VALENTINOVICH, TITOV, ILYA YURIEVICH, NOVIKOV, FEDOR NIKOLAEVICH, ZEIFMAN, ALEKSEY ALEXANDROVICH
Format Patent
LanguageEnglish
French
Published 28.03.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to novel chemical compounds of general formula I, in which L A, L B, L C, ring A, ring B, R A, R B, R C,R D,R E and R F have are defined in the description, and which are protein kinases inhibitors. The invention also relates to pharmaceutical compositions containing said compounds and also to the use of said compounds for treatment and/or prevention of diseases related with aberrant protein kinase activity. (see formula I)
Bibliography:Application Number: CA20142914717