3,4-DIHYDROISOQUINOLIN-2(1H)-YL COMPOUNDS

The invention provides certain 3,4-dihydroisoquinolin-2(1H)-yl compounds, particularly compounds of formula (I), and pharmaceutical compositions thereof. The invention further provides methods of using a compound of formula (I) to treat cognitive impairment associated with Parkinson's disease o...

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Main Authors HAO, JUNLIANG, SCHAUS, JOHN MEHNERT, BEADLE, CHRISTOPHER DAVID, WOLFANGEL, CRAIG DANIEL, KRUSHINSKI, JOSEPH HERMAN, JR, COATES, DAVID ANDREW, REINHARD, MATTHEW ROBERT
Format Patent
LanguageEnglish
French
Published 30.05.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides certain 3,4-dihydroisoquinolin-2(1H)-yl compounds, particularly compounds of formula (I), and pharmaceutical compositions thereof. The invention further provides methods of using a compound of formula (I) to treat cognitive impairment associated with Parkinson's disease or schizophrenia. L'invention concerne certains composés de 3,4-dihydroisoquinoléin-2(1H)-yle, notamment des composés de formule (I), et des compositions pharmaceutiques correspondantes. L'invention concerne en outre des procédés d'utilisation d'un composé de formule (I) pour traiter la déficience cognitive associée à la maladie de Parkinson ou à la schizophrénie.
Bibliography:Application Number: CA20142912849