ANTI ALPHA-GAL IGM MONOCLONAL ANTIBODY CAPABLE OF RECOGNISING CELLS INFECTED WITH THE HUMAN PAPILLOMAVIRUS, AND METHOD FOR OBTAINING SAME

The invention relates to the development of an Igm-type monoclonal antibody (AcMo) directed against a-Gal present in the membrane of cells infected with the human papillomavirus and to a diagnosis technique using labelling with fluorophore of protoporphyrin IX (PpIX). The invention also relates to t...

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Bibliographic Details
Main Authors MEDINA FLORES, YOLANDA, DE LEON RODRIGUEZ, IRMA, JUAREZ PALAFOX, SHARLLY RUBI, RAMON GALLEGOS, EVA, ZAVALA CARVALLO, ARACELI MARGARITA
Format Patent
LanguageEnglish
French
Published 03.04.2014
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
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Summary:The invention relates to the development of an Igm-type monoclonal antibody (AcMo) directed against a-Gal present in the membrane of cells infected with the human papillomavirus and to a diagnosis technique using labelling with fluorophore of protoporphyrin IX (PpIX). The invention also relates to the use of same as a method that is complementary to existing methods, offering increased specificity and sensitivity, for the in situ and in vivo diagnosis and treatment of patients with HPV.
Bibliography:Application Number: CA20122908415