SUBSTITUTED BIARYL COMPOUND

The present invention provides a substituted biaryl compound represented by general formula (I) (wherein R1, W, R2 and Z are as defined in the claims and the description) or a pharmacologically acceptable salt thereof. The compound according to the present invention has an excellent effect of inhibi...

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Main Authors KANDA, TOMOKO, USHIYAMA, SHIGERU, SHIBAKAWA, NOBUHIKO, IWASE, NORIAKI, YONEDA, KENJI, KATSUBE, TETSUSHI, YAMAMOTO, KIYOSHI, ITO, KOJI
Format Patent
LanguageEnglish
French
Published 02.10.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a substituted biaryl compound represented by general formula (I) (wherein R1, W, R2 and Z are as defined in the claims and the description) or a pharmacologically acceptable salt thereof. The compound according to the present invention has an excellent effect of inhibiting the proliferation of a pulmonary fibroblast, and is therefore useful as a therapeutic agent and/or a prophylactic agent for interstitial pneumonia and pulmonary fibrosis.
Bibliography:Application Number: CA20142908223