POSITIVE ALLOSTERIC MODULATORS OF MGLUR3

The present invention relates to novel substituted pyridine derivatives as positive allosteric modulators for modulating metabotropic giutamate receptor subtype 3 (mGluR3) and/or altering giutamate level or glutamatergic signalling. La présente invention concerne de nouveaux dérivés de pyridine subs...

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Bibliographic Details
Main Author POTNICK, JUSTIN
Format Patent
LanguageEnglish
French
Published 07.08.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to novel substituted pyridine derivatives as positive allosteric modulators for modulating metabotropic giutamate receptor subtype 3 (mGluR3) and/or altering giutamate level or glutamatergic signalling. La présente invention concerne de nouveaux dérivés de pyridine substitués en tant que modulateurs allostériques positifs pour la modulation du sous-type 3 du récepteur métabotropique du glutamate (mGluR3) et/ou pour la modification du taux de glutamate ou de la signalisation glutamatergique.
Bibliography:Application Number: CA20142899954