HUMANIZED MONOCLONAL ANTIBODIES AND METHODS OF USE FOR THE DIAGNOSIS AND TREATMENT OF COLON AND PANCREAS CANCER

This invention relates to humanized antibodies that selectively bind the 31.1 epitope on the A33 protein differentially expressed in cancers including, lung cancer, ovarian cancer, pancreas cancer, breast cancer and colon cancer, and diagnostic and therapeutic usages. La présente invention concerne...

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Bibliographic Details
Main Authors WANG, XUE-PING, ARLEN, PHILIP M
Format Patent
LanguageEnglish
French
Published 03.07.2014
Subjects
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Summary:This invention relates to humanized antibodies that selectively bind the 31.1 epitope on the A33 protein differentially expressed in cancers including, lung cancer, ovarian cancer, pancreas cancer, breast cancer and colon cancer, and diagnostic and therapeutic usages. La présente invention concerne des anticorps humanisés qui se lient sélectivement à l'épitope 31.1 de la protéine A33, différentiellement exprimée dans certains cancers, notamment le cancer du poumon, le cancer de l'ovaire, le cancer du pancréas, le cancer du sein et le cancer du côlon. L'invention concerne également des utilisations diagnostiques et thérapeutiques.
Bibliography:Application Number: CA20132896723