3-OXO-2,3,5,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3,A]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF INFLAMATORY RESPIRATORY DISORDERS

This invention relates to heterocyclic compounds of formual (I), which are pyrimidinone derivatives having human neutrophil elastase inhibitory properties, and their use in therapy (see formula I) Various different entities can be represented by the Groups A, B, D, R1, R2 and R3. L'invention co...

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Bibliographic Details
Main Authors ARMANI, ELISABETTA, ALCARAZ, LILIAN, HEALD, ROBERT ANDREW, SUTTON, JONATHAN MARK, CAPALDI, CARMELIDA
Format Patent
LanguageEnglish
French
Published 17.05.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention relates to heterocyclic compounds of formual (I), which are pyrimidinone derivatives having human neutrophil elastase inhibitory properties, and their use in therapy (see formula I) Various different entities can be represented by the Groups A, B, D, R1, R2 and R3. L'invention concerne des composés hétérocycliques de formule (I), qui sont des dérivés de la pyrimidinone présentant des propriétés d'inhibition de l'élastase neutrophile humaine, et leur utilisation thérapeutique Diverses entités peuvent être représentées par les groupes A, B, D, R1, R2 et RJ.
Bibliography:Application Number: CA20132895352