THERAPEUTICALLY ACTIVE PYRAZOLO-PYRIMIDINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYL-INOSITOL-4-KINASE IIIB (PI4KIIIB) ACTIVITY

A series of pyrazolo[3,4-d]pyrimidine derivatives that are substituted at the 4- position by a diaza monocyclic, bridged bicyclic or spirocyclic moiety, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral di...

Full description

Saved in:
Bibliographic Details
Main Authors HUANG, QIUYA, FORD, DANIEL JAMES, HORSLEY, HELEN TRACEY, GHAWALKAR, ANANT RAMRAO, FRANKLIN, RICHARD JEREMY, VANDERHOYDONCK, BART, REUBERSON, JAMES THOMAS
Format Patent
LanguageEnglish
French
Published 15.12.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:A series of pyrazolo[3,4-d]pyrimidine derivatives that are substituted at the 4- position by a diaza monocyclic, bridged bicyclic or spirocyclic moiety, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseasesand malaria; and organ and cell transplant rejection. Cette invention concerne une série de dérivés de pyrazolo[3,4-d]pyrimidine qui sont substitués à la position 4 par un fragment monocyclique, bicyclique ponté ou spirocyclique de type diaza, qui sont bénéfiques pour traiter et/ou prévenir diverses maladies humaines, comprenant les troubles inflammatoires, autoimmuns et oncologiques ; les maladies virales et le paludisme ; et le rejet de greffes d'organes et de cellules.
Bibliography:Application Number: CA20132893704