OLIGONUCLEOTIDE AND ARTIFICIAL NUCLEOSIDE HAVING GUANIDINE BRIDGE

This oligonucleotide or pharmaceutically acceptable salt thereof contains a compound represented by formula I or II or a salt thereof, and at least one nucleoside structure represented by formula I' or II'. Thus provided is a nucleic acid molecule for oligonucleotides having high specifici...

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Bibliographic Details
Main Authors WAKI, REIKO, KOTOBUKI, YUTARO, OBIKA, SATOSHI
Format Patent
LanguageEnglish
French
Published 27.03.2014
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
SUGARS
VINEGAR
WINE
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Summary:This oligonucleotide or pharmaceutically acceptable salt thereof contains a compound represented by formula I or II or a salt thereof, and at least one nucleoside structure represented by formula I' or II'. Thus provided is a nucleic acid molecule for oligonucleotides having high specificity and binding affinity to a target nucleic acid, and exhibiting high nuclease resistance.
Bibliography:Application Number: CA20132885719