PROCESS FOR THE PREPARATION OF PHOSPHONATE COMPOUNDS USEFUL IN THE PREPARATION OF HIMBACINE ANALOGS

This application discloses a process for the preparation of Compound 16 (see compound 16) The compound is useful for preparing himbacine analogs that are thrombin receptor antagonists. La présente invention a trait à un procédé pour la préparation du composé 16 (voir le composé 16). Le composé est u...

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Main Authors SUDHAKAR, ANANTHA, SABESAN, VIJAY, WU, GEORGE G, CUI, JIAN, THIRUVENGADAM, TIRUVETTIPURAM K, WANG, TAO, HUANG, MINGSHENG, ZAVIALOV, ILIA, CHEN, FRANK XING, NGUYEN, HOA N, YANG, XIAOJING, XIE, JI, LIM, NGIAP KIE, LIAO, JING, POIRIER, MARC, KWOK, DAW-LONG
Format Patent
LanguageEnglish
French
Published 06.03.2018
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:This application discloses a process for the preparation of Compound 16 (see compound 16) The compound is useful for preparing himbacine analogs that are thrombin receptor antagonists. La présente invention a trait à un procédé pour la préparation du composé 16 (voir le composé 16). Le composé est utile pour préparer des analogues de lhimbacine qui sont des antagonistes de récepteur de thrombine.
Bibliography:Application Number: CA20062875768