GLUCAGON-LIKE-PEPTIDE-2 (GLP-2) ANALOGUES

GLP-2 analogues are disclosed which comprise one of more substitutions as compared to h[Gly2]GLP-2 and which may have the property of an altered GLP-1 activity, and their medical use. The analogues are particularly useful for the prophylaxis, treatment or ameliorating of the gastro-intestinal associ...

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Bibliographic Details
Main Authors RUSSELL, WAYNE SHAUN, RIBER, DITTE, JUST, RASMUS, BOVBJERG, KIRSTEN LINDEGAARD
Format Patent
LanguageEnglish
French
Published 07.11.2013
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Summary:GLP-2 analogues are disclosed which comprise one of more substitutions as compared to h[Gly2]GLP-2 and which may have the property of an altered GLP-1 activity, and their medical use. The analogues are particularly useful for the prophylaxis, treatment or ameliorating of the gastro-intestinal associated side effects of diabetes. La présente invention concerne des analogues du GLP-2 qui comportent une ou plusieurs substitutions comparativement à h[Gly2]GLP-2 et qui pourraient présenter la propriété d'activité de GLP-1 modifiée, ainsi que leur usage médical. Les analogues sont particulièrement utiles pour la prophylaxie, le traitement ou l'amélioration des effets indésirables gastro-intestinaux du diabète.
Bibliography:Application Number: CA20132872315