ROD-LIKE HEPATITIS C VIRUS INHIBITORS CONTAINING THE FRAGMENT {2-[4-(BIPHENYL-4-YL)-1H-IMIDAZO-2-YL]PYRROLIDINE-1-CARBONLYMETHYL}AMINE

The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of replication of the hepatitis C virus. The invention also provides pharmaceutical compositions comprising such compounds, meth...

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Bibliographic Details
Main Authors MCKINNELL, ROBERT MURRAY, LONG, DANIEL D, ZHANG, WEIJIANG, JIANG, LAN, HUANG, XIAOJUN, LOO, MANDY, LEPACK, KASSANDRA, VAN ORDEN, LORI JEAN, OGAWA, GAVIN
Format Patent
LanguageEnglish
French
Published 10.05.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of replication of the hepatitis C virus. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat hepatitis C viral infections, and processes and intermediates useful for preparing such compounds.
Bibliography:Application Number: CA20122852700