5 - BENZYLAMINOMETHYL - 6 - AMINOPYRAZOLO [3,4-B] PYRIDINE DERIVATIVES AS CHOLESTERYL ESTER-TRANSFER PROTEIN (CETP) INHIBITORS USEFUL FOR THE TREATMENT OF ATHEROSCLEROSIS

The present application relates to a series of substituted pyrazolopyridin-6-amines having the general formula (I), including their stereoisomers and/or their pharmaceutically acceptable salts. (See Formula I) Wherein R, R1, R2, R a, R aa, R b and n are as defined herein. The present invention furth...

Full description

Saved in:
Bibliographic Details
Main Authors BORUAH, ANIMA, ALIKUNJU, SHANAVAS
Format Patent
LanguageEnglish
French
Published 01.05.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present application relates to a series of substituted pyrazolopyridin-6-amines having the general formula (I), including their stereoisomers and/or their pharmaceutically acceptable salts. (See Formula I) Wherein R, R1, R2, R a, R aa, R b and n are as defined herein. The present invention further relates to pharmaceutical compositions comprising compounds of formula (I). The compounds of this application are useful as CETP inhibitors for increasing HDL cholesterol and decreasing LDL cholesterol in a patient.
Bibliography:Application Number: CA20122850022