DELIVERY AND FORMULATION OF ENGINEERED NUCLEIC ACIDS

Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins. L'invention conc...

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Main Authors AFEYAN, NOUBAR B, ELBASHIR, SAYDA M, SCHRUM, JASON P, SIECZKIEWICZ, GREGORY J, DE FOUGEROLLES, ANTONIN, BANCEL, STEPHANE
Format Patent
LanguageEnglish
French
Published 04.10.2012
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
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Summary:Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins. L'invention concerne des formulations, des compositions et des procédés d'administration de fractions biologiques, telles que des acides nucléiques modifiés, dans des cellules pour moduler l'expression protéique. De telles compositions et de tels procédés comprennent l'administration de fractions biologiques et sont utiles pour la production de protéines.
Bibliography:Application Number: CA20122831613