HETEROARYL COMPOUNDS AS 5-HT4 RECEPTOR LIGANDS

• Main Authors: YARLAGADDA, SURESH, ROAYAPALLEY, PRAVEEN KUMAR, MOHAMMED, ABDUL RASHEED, JAYARAJAN, PRADEEP, RAVELLA, SRINIVASA RAO, JASTI, VENKATESWARLU, NIROGI, RAMAKRISHNA, KAMBHAMPATI, RAMASASTRI, PATNALA, SRIRAMACHANDRA MURTHY, SHINDE, ANIL KARBHARI, BHYRAPUNENI, GOPINADH, RAVULA, JYOTHSNA
• Format: Patent
• Language: English; French
• Published: 27.10.2015
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to novel compounds of formula (I), and their pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, and their pharmaceutically acceptable salts. The compounds of formula (I) are useful in the treatment of various disorders that are related to 5-HT4 receptors. La présente invention concerne, d'une part de nouveaux composés représentés par la formule (I), d'autre part leurs sels pharmaceutiquement admis, et enfin des compositions les contenant. L'invention concerne également un procédé d'élaboration de ces composés et de leurs sels pharmaceutiquement admis. Les composés représentés par la formule (I) conviennent au traitement de divers troubles dans lesquels interviennent les récepteurs 5-HT4.