4-SUBSTITUTED-3-BENZYLOXY-BICYCLO[3.1.0]HEXANE COMPOUNDS AS MGLUR 2/3 ANTAGONISTS

The present invention relates to an mGlu2/3 receptor antagonist of Formula (I): (see formula I) its uses, including in treatment of depressive disorders and disorders of excessive sleepiness. Methods for preparation of the said receptor antagonist are also described in the present application. L...

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Main Authors TROMICZAK, ERIC GEORGE, CHAPPELL, MARK DONALD, DRESSMAN, BRUCE ANTHONY, ORNSTEIN, PAUL LESLIE, FIVUSH, ADAM MICHAEL, VETMAN, TATIANA NATALI, MITCH, CHARLES HOWARD
Format Patent
LanguageEnglish
French
Published 29.03.2016
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to an mGlu2/3 receptor antagonist of Formula (I): (see formula I) its uses, including in treatment of depressive disorders and disorders of excessive sleepiness. Methods for preparation of the said receptor antagonist are also described in the present application. L'invention concerne un antagoniste du récepteur mGlu2/3 de la formule : ses utilisations, ainsi que des procédés pour sa préparation.
Bibliography:Application Number: CA20112818118