N1/N2-LACTAM ACETYL-COA CARBOXYLASE INHIBITORS

The invention provides a compound of Formula (I); or a pharmaceutically acceptable salt thereof; wherein G is Formula (II), Formula (III), Formula (IV) and Formula (V) R1, R2 and R3 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or...

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Bibliographic Details
Main Authors GRIFFITH, DAVID ANDREW, DOW, ROBERT LEE, SMITH, AARON CHRISTOPHER, BAGLEY, SCOTT WILLIAM
Format Patent
LanguageEnglish
French
Published 06.10.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention provides a compound of Formula (I); or a pharmaceutically acceptable salt thereof; wherein G is Formula (II), Formula (III), Formula (IV) and Formula (V) R1, R2 and R3 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase enzyme(s) in an animal. La présente invention concerne un composé de formule (I) ou un sel pharmaceutiquement acceptable de celui-ci. Dans la formule (I), G représente un composé de formule (II), de formule (III), de formule (IV) ou de formule (V) et R1, R2 et R3 sont tels que décrits ici. L'invention concerne également des compositions pharmaceutiques contenant ledit composé de formule (I) et leur utilisation dans le cadre du traitement de maladies, d'affections ou de troubles modulés par l'inhibition d'une ou plusieurs enzymes de type acétyl-CoA carboxylase, chez un animal.
Bibliography:Application Number: CA20112815169