MARKERS FOR RENAL DISEASE

This invention provides reagents and methods for diagnosing renal disease. Differential levels of inosine metabolite, and proteins: apolipoprotein C-I, apolipoprotein C-II, fibrinogen alpha chain, or fibrinogen A-alpha chain, kininogen, Inter-Alpha Inhibitor H4 (ITIH4), keratin Type I cytoskeletol 1...

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Bibliographic Details
Main Authors YERRAMILLI, MURTHY V. S. N, YERRAMILLI, MAHALAKSHMI, ATKINSON, MICHAEL RANDOLPH
Format Patent
LanguageEnglish
French
Published 10.03.2020
Subjects
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Summary:This invention provides reagents and methods for diagnosing renal disease. Differential levels of inosine metabolite, and proteins: apolipoprotein C-I, apolipoprotein C-II, fibrinogen alpha chain, or fibrinogen A-alpha chain, kininogen, Inter-Alpha Inhibitor H4 (ITIH4), keratin Type I cytoskeletol 10 cystatin A, cystatin B and other polypeptides and fragments thereof provide biomarkers of renal disease and are described herein. La présente invention concerne des réactifs et des procédés pour diagnostiquer une néphropathie. Plus spécifiquement, des niveaux différentiels du métabolite inosine et des protéines : apolipoprotéine C-I, apolipoprotéine C-II, chaîne alpha du fibrinogène ou chaîne A-alpha du fibrinogène, kininogène, inhibiteur inter-alpha H4 (ITIH4), cytokératine-10 de type I, cystatine A, cystatine B, et d'autres polypeptides et de fragments de ceux-ci fournissent des biomarqueurs de néphropathies.
Bibliography:Application Number: CA20112799536