PROGESTERONE RECEPTOR ANTAGONISTS

The invention relates to 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl derivatives of formula (I) exhibiting progesterone-antagonistic effects and to methods for the production thereof, to the use thereof for the treatment and/or prevention of diseases and to the use thereof for producing...

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Bibliographic Details
Main Authors KLAR, ULRICH, MOELLER, CARSTEN, SCHWEDE, WOLFGANG, ROTGERI, ANDREA, BONE, WILHELM, HUWE, CHRISTOPH
Format Patent
LanguageEnglish
French
Published 18.08.2011
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
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Summary:The invention relates to 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl derivatives of formula (I) exhibiting progesterone-antagonistic effects and to methods for the production thereof, to the use thereof for the treatment and/or prevention of diseases and to the use thereof for producing medicaments for the treatment and/or prevention of diseases, in particular uterine fibroids (myomas, uterine leiomyomas), endometriosis, menorrhagia, meningiomas, hormone-dependent mammary carcinomas and menopause- associated troubles or for fertility control and emergency contraception.
Bibliography:Application Number: CA20112789240