CHOLINE SALT OF FUSED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

An objective of the present invention is to improve the solubility of 3 - [2-fluoro-5 -(2,3 -difluoro-6-methoxybenzyloxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid. The present invention provides 3 - [2 -fluoro-5 -(2,3 -difluoro-6-methoxybenzyloxy)-4-meth...

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Bibliographic Details
Main Authors TAKEUCHI, HIDEKI, JO, KAZUMICHI
Format Patent
LanguageEnglish
French
Published 06.03.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:An objective of the present invention is to improve the solubility of 3 - [2-fluoro-5 -(2,3 -difluoro-6-methoxybenzyloxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid. The present invention provides 3 - [2 -fluoro-5 -(2,3 -difluoro-6-methoxybenzyloxy)-4-methoxyphenyl] -2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid choline salt has excellent solubility and storage stability.
Bibliography:Application Number: CA20112788533