METHODS FOR DETERMINING FRACTION OF FETAL NUCLEIC ACID IN MATERNAL SAMPLES

The invention provides compositions and methods for determining the fraction of fetal nucleic acids in a maternal sample comprising a mixture of fetal and maternal nucleic acids. The fraction of fetal nucleic acids can be used in determining the presence or absence of fetal aneuploidy. L'invent...

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Bibliographic Details
Main Authors COMSTOCK, DAVID A, RAVA, RICHARD P, HEILEK, GABRIELLE, CHUU, YUE-JEN, HUNKAPILLER, MICHAEL, CHINNAPPA, MANJULA
Format Patent
LanguageEnglish
French
Published 04.04.2017
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMBINATORIAL CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Summary:The invention provides compositions and methods for determining the fraction of fetal nucleic acids in a maternal sample comprising a mixture of fetal and maternal nucleic acids. The fraction of fetal nucleic acids can be used in determining the presence or absence of fetal aneuploidy. L'invention concerne des compositions et des procédés pour déterminer la fraction d'acides nucléiques ftaux dans un échantillon maternel comprenant un mélange d'acides nucléiques ftaux et maternels. La fraction d'acides nucléiques ftaux peut être utilisée dans la détermination de la présence ou l'absence d'aneuploïdie ftale.
Bibliography:Application Number: CA20102785718