FORMULATIONS SUITABLE FOR PET IMAGING WITH HYDROPHOBIC PET AGENTS

The invention is directed to formulations of lipophilic Amyloid ßeta ligand stilbene based derivatives and more particularly to formulations which are administrable parentally e.g. intravenously wherein the lipophilic Amyloid ßeta ligand stilbene based derivative is a 19F or 18F-labeled radiopharmac...

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Bibliographic Details
Main Authors BURKHARD, ANDREAS, OLBRICH, CARSTEN, KRAUSE, MICHAEL
Format Patent
LanguageEnglish
French
Published 05.12.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention is directed to formulations of lipophilic Amyloid ßeta ligand stilbene based derivatives and more particularly to formulations which are administrable parentally e.g. intravenously wherein the lipophilic Amyloid ßeta ligand stilbene based derivative is a 19F or 18F-labeled radiopharmaceutical thereof. Further, the invention is directed to a method for sterile filtration of said suitable formulation. Cette invention concerne des formulations de dérivés lipophiles à base de stilbène utilisées à titre de ligands de l'amyloïde ß, en particulier, des formulations qui peuvent être administrées par voie parentérale, par exemple, par voie intraveineuse, le dérivé lipophile à base de stilbène utilisé à titre de ligand de l'amyloïde ß étant un radiopharmaceutique de celui-ci marqué au 19F ou au 18F. L'invention concerne, en outre, un procédé de filtration stérile de ladite formulation adaptée.
Bibliography:Application Number: CA20102785576