MODULATORS OF TNF-.ALPHA. SIGNALING

The present invention provides compounds which are modulators of TNF.alpha. signaling and methods of use thereof for treating a patient having a TNF-.alpha. mediated condition. The compounds can be represented by structural formulas (I), (II) and (III).

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Bibliographic Details
Main Authors JANJIGIAN, ANDREW, NAHILL, SHARON R, VINICK, FRED, HIRTH, BRADFORD H, WILLIAMS, JOHN M, BIEMANN, HANS-PETER, SNEDDON, SCOTT F, QIAO, SHUANG, KANE, JOHN L
Format Patent
LanguageEnglish
French
Published 31.03.2015
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides compounds which are modulators of TNF.alpha. signaling and methods of use thereof for treating a patient having a TNF-.alpha. mediated condition. The compounds can be represented by structural formulas (I), (II) and (III).
Bibliography:Application Number: CA20012781858