LABELED MOLECULAR IMAGING AGENTS, METHODS OF MAKING AND METHODS OF USE

Imaging agents that com-prise labeled substrates of the cystine/glutamate antiporter of cells, whereby the methods of use comprise introducing the labeled agents into cells via the cystine/glutamate antiporter, which are then reduced to a labeled cys-teine, and subsequently detected in the cell.

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Bibliographic Details
Main Authors AMARASINGHE, KANDE KANKANAMALAGE DAYARA, SCHAFFER, PAUL, HUNTINGTON, JENNIFER, WEBSTER, JACK MATHEW, SYUD, FAISAL AHMED, LEE, BRIAN DUH-LAN, ZHANG, RONG
Format Patent
LanguageEnglish
French
Published 08.08.2017
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Imaging agents that com-prise labeled substrates of the cystine/glutamate antiporter of cells, whereby the methods of use comprise introducing the labeled agents into cells via the cystine/glutamate antiporter, which are then reduced to a labeled cys-teine, and subsequently detected in the cell.
Bibliography:Application Number: CA20102759000