OSTEOARTHRITIS GENE THERAPY

The present invention relates to methods and compositions for protecting joint cartilage from degradation by inserting transgenes that increase Kras-2b expression or an effector thereof within one or more tissues of the joint. The present invention can thus be used in the treatment and/or prevention...

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Bibliographic Details
Main Author GOOMER, RANDAL S
Format Patent
LanguageEnglish
French
Published 07.05.2009
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to methods and compositions for protecting joint cartilage from degradation by inserting transgenes that increase Kras-2b expression or an effector thereof within one or more tissues of the joint. The present invention can thus be used in the treatment and/or prevention of joint diseases and disorders, including but not limited to osteoarthritis.
Bibliography:Application Number: CA20082739011