TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS

Compounds of Formula (I), in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of immune cell-associated diseases and disorders, such as inflammatory and autoimmune diseases. La présente invention co...

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Main Authors LYSSIKATOS, JOSEPH P, MUNSON, MARK C, RAST, BRYSON, DELISLE, ROBERT KIRK, GROSS, STEFAN D, DAVIS, T. GREGG, MARMSAETER, FREDRIK P, TOPALOV, GEORGE T, HICKEN, ERIK JAMES, WRIGHT, A. DALE, CELESTE, LAURA L, ROBINSON, JOHN E, ZHAO, QIAN, KALLAN, NICHOLAS C, PHENEGER, JED, GRESCHUK, JULIE MARIE, ALLEN, SHELLEY, JACKSON, LEILA J, SCHLACHTER, STEPHEN T
Format Patent
LanguageEnglish
French
Published 18.04.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Compounds of Formula (I), in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of immune cell-associated diseases and disorders, such as inflammatory and autoimmune diseases. La présente invention concerne les composés de formule (I), dans laquelle A, B, R1, R1a, R2, R3, R4, R5, R6, et R7 ont les significations données dans la spécification, qui sont des inhibiteurs de la tyrosine du récepteur utiles dans le traitement de maladies et troubles associés aux cellules immunitaires, tels que les maladies inflammatoires et auto-immunes.
Bibliography:Application Number: CA20092734831