PROTECTIVE GEL BASED ON CHITOSAN AND OXIDIZED POLYSACCHARIDE

Bodily tissue and structures may be protected using a fluid layer containing a mixture of chitosan and oxidized polysaccharide. The mixture forms a protective gel layer via in situ crosslinking. Compared to crosslinking using a low molecular weight aldehyde such as glutaraldehyde or genipin, oxidize...

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Bibliographic Details
Main Authors SCHAFAUSEN, NANCY, GONZALEZ, MARIA NIEVES, TIJSMA, EDZE JAN, TENBROEK, ERICA M
Format Patent
LanguageEnglish
French
Published 29.10.2009
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Bodily tissue and structures may be protected using a fluid layer containing a mixture of chitosan and oxidized polysaccharide. The mixture forms a protective gel layer via in situ crosslinking. Compared to crosslinking using a low molecular weight aldehyde such as glutaraldehyde or genipin, oxidized polysaccharides appear to provide faster gelation while avoiding the use of potentially less bioacceptable low molecular weight aldehydes.
Bibliography:Application Number: CA20092721937