ORAL PHARMACEUTICAL COMPOSITIONS IN A MOLECULAR SOLID DISPERSION
The present invention provides a solid molecularly dispersed composition comprising a poorly water soluble and weakly basic azole antifungal compound and a pH sensitive polymer, pharmaceutical compositions, comprising the solid molecularly dispersed composition of the invention and methods of treati...
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Format | Patent |
Language | English French |
Published |
22.10.2009
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Abstract | The present invention provides a solid molecularly dispersed composition comprising a poorly water soluble and weakly basic azole antifungal compound and a pH sensitive polymer, pharmaceutical compositions, comprising the solid molecularly dispersed composition of the invention and methods of treating and/or preventing a fungal infection in a patient in need thereof comprising orally administering a pharmaceutical composition comprising a composition of the invention to a patient in need thereof. Preferably the antifungal, compound is posaconazole, and the pH sensitive polymer is HPMCAS. |
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AbstractList | The present invention provides a solid molecularly dispersed composition comprising a poorly water soluble and weakly basic azole antifungal compound and a pH sensitive polymer, pharmaceutical compositions, comprising the solid molecularly dispersed composition of the invention and methods of treating and/or preventing a fungal infection in a patient in need thereof comprising orally administering a pharmaceutical composition comprising a composition of the invention to a patient in need thereof. Preferably the antifungal, compound is posaconazole, and the pH sensitive polymer is HPMCAS. |
Author | FANG, LARRY YUN WAN, JIANSHENG HARRIS, DAVID |
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DocumentTitleAlternate | COMPOSITIONS PHARMACEUTIQUES ORALES DANS UNE DISPERSION SOLIDE MOLECULAIRE |
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Snippet | The present invention provides a solid molecularly dispersed composition comprising a poorly water soluble and weakly basic azole antifungal compound and a pH... |
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Title | ORAL PHARMACEUTICAL COMPOSITIONS IN A MOLECULAR SOLID DISPERSION |
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