ORAL PHARMACEUTICAL COMPOSITIONS IN A MOLECULAR SOLID DISPERSION
The present invention provides a solid molecularly dispersed composition comprising a poorly water soluble and weakly basic azole antifungal compound and a pH sensitive polymer, pharmaceutical compositions, comprising the solid molecularly dispersed composition of the invention and methods of treati...
Saved in:
| Main Authors | , , |
|---|---|
| Format | Patent |
| Language | English French |
| Published |
22.10.2009
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The present invention provides a solid molecularly dispersed composition comprising a poorly water soluble and weakly basic azole antifungal compound and a pH sensitive polymer, pharmaceutical compositions, comprising the solid molecularly dispersed composition of the invention and methods of treating and/or preventing a fungal infection in a patient in need thereof comprising orally administering a pharmaceutical composition comprising a composition of the invention to a patient in need thereof. Preferably the antifungal, compound is posaconazole, and the pH sensitive polymer is HPMCAS. |
|---|---|
| AbstractList | The present invention provides a solid molecularly dispersed composition comprising a poorly water soluble and weakly basic azole antifungal compound and a pH sensitive polymer, pharmaceutical compositions, comprising the solid molecularly dispersed composition of the invention and methods of treating and/or preventing a fungal infection in a patient in need thereof comprising orally administering a pharmaceutical composition comprising a composition of the invention to a patient in need thereof. Preferably the antifungal, compound is posaconazole, and the pH sensitive polymer is HPMCAS. |
| Author | FANG, LARRY YUN WAN, JIANSHENG HARRIS, DAVID |
| Author_xml | – fullname: WAN, JIANSHENG – fullname: FANG, LARRY YUN – fullname: HARRIS, DAVID |
| BookMark | eNrjYmDJy89L5WRw8A9y9FEI8HAM8nV0dg0N8XQGcp39fQP8gz1DPP39ghU8_RQcFXz9fVydQ30cgxSC_X08XRRcPIMDXIOCgQp4GFjTEnOKU3mhNDeDgptriLOHbmpBfnxqcUFicmpeakm8s6ORuZGBhamho6ExEUoAemksDA |
| ContentType | Patent |
| DBID | EVB |
| DatabaseName | esp@cenet |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry Sciences |
| DocumentTitleAlternate | COMPOSITIONS PHARMACEUTIQUES ORALES DANS UNE DISPERSION SOLIDE MOLECULAIRE |
| ExternalDocumentID | CA2720851A1 |
| GroupedDBID | EVB |
| ID | FETCH-epo_espacenet_CA2720851A13 |
| IEDL.DBID | EVB |
| IngestDate | Fri Jul 19 16:01:36 EDT 2024 |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | false |
| Language | English French |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-epo_espacenet_CA2720851A13 |
| Notes | Application Number: CA20092720851 |
| OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20091022&DB=EPODOC&CC=CA&NR=2720851A1 |
| ParticipantIDs | epo_espacenet_CA2720851A1 |
| PublicationCentury | 2000 |
| PublicationDate | 20091022 |
| PublicationDateYYYYMMDD | 2009-10-22 |
| PublicationDate_xml | – month: 10 year: 2009 text: 20091022 day: 22 |
| PublicationDecade | 2000 |
| PublicationYear | 2009 |
| RelatedCompanies | SCHERING CORPORATION |
| RelatedCompanies_xml | – name: SCHERING CORPORATION |
| Score | 2.755629 |
| Snippet | The present invention provides a solid molecularly dispersed composition comprising a poorly water soluble and weakly basic azole antifungal compound and a pH... |
| SourceID | epo |
| SourceType | Open Access Repository |
| SubjectTerms | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| Title | ORAL PHARMACEUTICAL COMPOSITIONS IN A MOLECULAR SOLID DISPERSION |
| URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20091022&DB=EPODOC&locale=&CC=CA&NR=2720851A1 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3NS8MwFH-MKepNp-L8IgfprejWrKaHolnaskm7lG6V3cbSD9ilG67iv28S1ulFbyGBx0vgfeWX9wvAw7JUcczBZiGcZxMXJDOXvTI3M4JFb0kwyYVCdKOJPUrx23wwb8Gq6YXRPKFfmhxRWlQm7b3W_nrzc4nl6beV20exklPrl2DmekZTHTuqgDG8oevH3OPMYMxl1JgkroIbZXJBZaF0oLJoRbPvvw9VU8rmd0QJTuEwlsKq-gxaRdWBY9Z8vNaBo2iHd8vhzvS25_DKExqieESTiDI_nSkeA8R4FPPpWLcCo_EEURTx0GdpSBM05eHYQ-p1iJ8oj3kBKPBnbGRKVRb7bS8Y3SttXUK7WlfFFSCZ3pSKdawc2BbOsC3yUlY0FhG2IPkTcbrQ_VPM9T9rN3CigRLplvv9W2jXH5_FnYy3tbjXJ_UNOL1-aQ |
| link.rule.ids | 230,309,786,891,25594,76903 |
| linkProvider | European Patent Office |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3NT8IwFH8haMSbokb87MHstihQRndYtHQjm-4rYxhuhO4j4TKIzPjv2zaAXvTWtMnLa5P38euv7xXgYVHKOGZiveDmUMcFyfRFt8z1jGDeXRBMci4Z3SA03Cl-nQ1mDVjuamFUn9Av1RxRWFQm7L1W_nr9c4llq7eVm0e-FFOr53Fq2doOHZsSwGj2yHLiyI6YxpjFqBYmlqQbRXJBBVA6GApEqJDS-0gWpax_R5TxCRzGQlhVn0KjqNrQYruP19pwFGz5bjHcmt7mDF6ihPoodmkSUOZMU9nHALEoiKOJp0qBkRciioLId9jUpwmaRL5nI_k6xEmkxzwHNHZS5upClfl-23NG90r3L6BZrariEpBIb0rZdawcGH2cYYPnpUA0fcINTvInYnag86eYq3_W7qHlpoE_973w7RqOFWkiXHSvdwPN-uOzuBWxt-Z36tS-AUbfgVM |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=ORAL+PHARMACEUTICAL+COMPOSITIONS+IN+A+MOLECULAR+SOLID+DISPERSION&rft.inventor=WAN%2C+JIANSHENG&rft.inventor=FANG%2C+LARRY+YUN&rft.inventor=HARRIS%2C+DAVID&rft.date=2009-10-22&rft.externalDBID=A1&rft.externalDocID=CA2720851A1 |