ORAL PHARMACEUTICAL COMPOSITIONS IN A MOLECULAR SOLID DISPERSION
The present invention provides a solid molecularly dispersed composition comprising a poorly water soluble and weakly basic azole antifungal compound and a pH sensitive polymer, pharmaceutical compositions, comprising the solid molecularly dispersed composition of the invention and methods of treati...
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Main Authors | , , |
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Format | Patent |
Language | English French |
Published |
22.10.2009
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention provides a solid molecularly dispersed composition comprising a poorly water soluble and weakly basic azole antifungal compound and a pH sensitive polymer, pharmaceutical compositions, comprising the solid molecularly dispersed composition of the invention and methods of treating and/or preventing a fungal infection in a patient in need thereof comprising orally administering a pharmaceutical composition comprising a composition of the invention to a patient in need thereof. Preferably the antifungal, compound is posaconazole, and the pH sensitive polymer is HPMCAS. |
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Bibliography: | Application Number: CA20092720851 |