OPHTHALMIC COMPOSITIONS WITH AN AMPHOTERIC SURFACTANT AND HYALURONIC ACID

Ophthalmic compositions that comprise 0.1 ppm to 10 ppm of a cationic antimicrobial component selected from the group consisting of biguanides, polymeric biguanides, quaternium ammonium compounds and any one mixture thereof; 0.005 wt.% to 0.15 wt.% of hyaluronic acid; and 0.01 wt.% to 1.0 wt.% of an...

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Bibliographic Details
Main Authors VENKATESH, SRINI, BARNIAK, VICKI L, XIA, ERNING, BURKE, SUSAN E
Format Patent
LanguageEnglish
French
Published 06.08.2009
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Ophthalmic compositions that comprise 0.1 ppm to 10 ppm of a cationic antimicrobial component selected from the group consisting of biguanides, polymeric biguanides, quaternium ammonium compounds and any one mixture thereof; 0.005 wt.% to 0.15 wt.% of hyaluronic acid; and 0.01 wt.% to 1.0 wt.% of an amphoteric surfactant of general formula I wherein R1 is R or -(CH2)n-NHC(O)R, wherein R is a C8-Ci6alkyl optionally substituted with hydroxyl and n is 2, 3 or 4; R2 and R3 are each independently selected from methyl, ethyl, propyl or iso-propyl; and R4 is a C2-C8alkylene optionally substituted with hydroxyl. The invention is also direct to the use of the ophthalmic compositions to clean and disinfect contact lenses, and in particular, soft, silicone hydrogel contact lenses.
Bibliography:Application Number: CA20082713308